Lars von Trier directs this sci-fi drama about the effects of depression on two sisters, Justine (Kirsten Dunst) and Claire (Charlotte Gainsbourg). Played out in two acts, Melancholia opens with the wedding of Justine (Dunst) and Michael (Alexander Skarsgard): a sumptuous affair paid for by Justine's Claire (Charlotte Gainsbourg) and her husband John (Kiefer Sutherland). However, when Justine notices a strange star in the sky, she starts behaving oddly and the wedding is ruined. The film's second act follows Justine, now extremely weak and ill, after she goes to live with her sister. As Claire and John struggle to deal with Justine's condition, astronomy buff Claire becomes increasingly concerned about a large blue planet that is threatening to collide with the earth.

Cast:
Kirsten Dunst, Charlotte Gainsbourg, Kiefer Sutherland, Charlotte Rampling, John Hurt, Alexander Skarsgård